It’s that time of year again.

Colors are changing, leaves are falling, temperatures are dropping and two Twin Cities brewers are preparing for the next brew-off.

The quarterly competition, started by Tin Whiskers in May 2015, will take place on Thursday, Sept. 29 at Moto-i in Minneapolis’ Uptown neighborhood.

This time, British-inspired Northeast brewery Northgate will take on St. Paul’s Tin Whiskers.

As with previous brew-offs, patrons will blind taste-test two beers, one brewed by each brewery. Both beers will incorporate fan-chosen ingredients – rhubarb, lingonberry and ancho chile – but can be any style the brewer chooses.

“This is a really fun way to collaborate with others in the industry because we both have a great passion for experimentation,” Jeff Moriarty, President and Founder of Tin Whiskers Brewing, said in a recent press release. “The Brew-Off is intended…to challenge ourselves and use ingredients we may never have used before.”

Patrons will vote for which beer they like best, and by the end of the night a winner will be chosen.

The brew-off runs from 5 to 8 p.m.

Moto-i is located at 2940 Lyndale Avenue, near the intersection of Lake Street and Lyndale Avenue. Street parking is available. For those who may not want to drive, Metro Transit Bus routes 4, 21, 53, 113 drop off at the intersection of Lake Street and Lyndale Avenue.