Moonves, 68, has run CBS since 2006 and his exit marked a dramatic fall by one by the most powerful executives in Hollywood. Moonves and Chen have been married since 2004.
The allegations, reported by Ronan Farrow, include forced kissing, forced oral sex, unwanted advances and physical abuse. Some of the women say Moonves retaliated against them and that their careers suffered after they rebuffed his advances.
Moonves has denied the allegations.