CHICAGO (AP) — Nearly 500 flights have been cancelled on one of the busiest travel days of the year as a fast-moving winter storm bears down on much of the Midwest on the last day of the Thanksgiving holiday weekend.

The flight-tracking website FlightAware reported that 491 flights headed to or from the U.S. had been cancelled as of 11 a.m. Sunday.

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The site reported that the majority of the cancellations are flights that were supposed to be routed through Chicago or Kansas City — two areas forecast to be hit hard by the storm.

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The National Weather Service has issued a blizzard warning for parts of Nebraska, Kansas, Missouri and Iowa. Other parts of central plains and Great Lakes region are under a winter storm warning.

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